Jon Levine, PhD

Title: Professor; Director – Wisconsin National Primate Research Center
Department: Neuroscience
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PubMed Publications


BA 1976 Oberlin College, Oberlin, OH
PhD 1982 University of Illinois, Urbana, IL
1st Postdoctoral position: Oregon National Primate Research Center & Oregon Health Sciences University


Research Focus

For the past 30 years I have studied the neuroendocrine regulation of gonadotropin releasing hormone (GnRH) neurons, in part by developing and utilizing physiological methods to monitor and analyze GnRH neurosecretion in awake animals. My research has also focused on the mechanisms by which ovarian steroids exert their effects in the brain, the latter including the negative feedback mechanisms that maintain homeostatic control within the reproductive axis, as well as the positive feedback actions of steroids that culminate in release of preovulatory gonadotropin surges. My recent work has made use of newly developed mutant mice to analyze the cell signaling mechanisms that mediate negative and positive feedback actions of estradiol.

Program Activities

  • Joined ERP Program: 2010
  • Committees
    • Member – ERP Program Steering Committee

Research Funding

  • Director, WNPRC NIH/OD P51 OD011106-53 07/02/13 – 04/30/17
  • Center Co-Director and Principal Investigator of Project III NIH/NICHD P50 HD44405-12 07/01/13 – 06/30/17 Genes, Androgens and Intrauterine Environment in PCOS
  • PI NIH/NICHD R01 HD068777-03 03/30/12 – 02/28/17 Sex steroids, kisspeptin, and regulation of GnRH
  • PI NIH/NICHD U54 HD028934-21 04/01/14 – 03/31/19 Clinical and Basic Studies in Polycystic Ovarian Syndrome (RFA-HD-14-017)



Current Trainees Degree Goal
No current ERP Students
Past Trainees Degree Completed