Biography NIH Biosketch PubMed Publications Departmental Website Research Focus Dr. Wiltbank studies the regulation of ovarian function. Basic studies focus on the regulation of hormonal receptors in the corpus luteum and developing ovarian follicle. Applied studies focus on development of methods that allow timed artificial insemination and improve pregnancy rates in dairy cattle. Program Activities …
Biography NIH Biosketch PubMed Publications Departmental Website Research Focus My laboratory is focused on the transcriptional regulation of estrogen receptor (ER) signaling pathways by nuclear receptor co-factors. Estrogen receptors regulate cell proliferation, differentiation and cell cycle control in a cell- and tissue-specific manner. The effect of estrogen in etiology and progression of breast cancer is …
Biography NIH Biosketch PubMed Publications Department Website Research Focus: Our research program focuses on elucidating how intestinal lipid metabolism modulates systemic energy balance and glycemic control. Using genetically engineered mice, we are exploring cellular and molecular mechanisms underlying the physiological functions of the intestine and the roles of the gut microbiome in health and disease. …
Biography PubMed Publications Departmental Website Research Focus Our lab aims to understand cellular and molecular mechanisms underlying sexual differentiation of reproductive tracts. Before sexual differentiation, both primitive male and female reproductive tracts co-exist in an embryo. During sexual differentiation, the embryo eliminates one of the two primitive reproductive tracts and maintains exclusively the one matching …
Biography NIH Biosketch PubMed Publications Departmental Website Research Focus My current research directions are to investigate mechanisms governing actions of angiogenic factors on fetoplacental vasculature with a specific interest in the intracellular signaling pathways. Specific research projects include 1) determining whether in the fetoplacenta bFGF- & VEGF-induced angiogenesis is modulated in part via an increase …