Tanja Dominko
Position title: Professor of Surgery/Transplantation
Email: dominko@wisc.edu
Phone: Effects of tissue environment on fibroblast behaviors during wound healing
Address:
Education
D.V.M. Veterinary Medicine, University of Ljubljana School of Veterinary Medicine, Ljubljana, Slovenia
M.S. Reproduction and Obstetrics, University of Ljubljana School of Veterinary Medicine, Ljubljana, Slovenia
Ph.D. Endocrinology-Reproductive Physiology, University of Wisconsin-Madison, Madison, WI
Postdoctoral fellow, Oregon National Primate Research Center
NIH Biosketch
PubMed Publications
Department Website
Research Focus:
The Dominko Lab focuses on the effects of tissue environment on fibroblast behaviors during wound healing. We are interested in the molecular mechanisms responsible for oxygen and growth factor signaling during switching between pro-fibrotic and pro-regenerative cell phenotype, the role of extracellular matrix in cell fate determination, and cell-cell and cell-material interactions in three-dimensional tissue constructs. Our goals are to better understand the pathways leading to functional tissue regeneration, develop clinically relevant therapies for regenerative medicine, and accelerate translation of promising discoveries into large animal models. We collaborate on development of humanized swine (organ donors for xenotransplantation) using assistive reproductive technologies, iPS cells, gene-editing and embryo complementation.
Program Activities
- Joined ERP Program: 2024
Trainees
No current or prior ERP students